Gene Architecture
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EXON 01 // MECHANICS
Sequence Strand | Splicing Mechanics Part 1
Section 1: The Spliceosome
Pre-mRNA
Unprocessed Transcript
The Pre-mRNA Transcript
Before splicing can occur, the raw RNA transcript contains both coding Exons and a non-coding Intron. The sequence contains specific chemical signposts: a 5' Splice Site (GU), a Branch Point Sequence (A), and a 3' Splice Site (AG).
Key Components
U1 (5' Reader)
U2 (BPS Reader)
U4 (Inhibitor)
U5 (Exon Bridge)
U6 (Catalyst)
SF1 / U2AF
EXON 02 // LOGIC LAB
Transcriptional Logic
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EXON 03 // EPIGENETICS
Chromatin Folding
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Sequence Complete
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